Browsing Doctoral Dissertations by Submit Date
Now showing items 1-20 of 31
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Kajian Ekstrak Kloroform : Metanol Xylocarpus granatum J. Koenig terhadap Regulasi Quorum Sensing Pseudomonas aeruginosa dan Methicillin-Resistant Staphylococcus aureus (MRSA)
(Universitas Sumatera Utara, 2025)Background: Pseudomonas aeruginosa and Methicillin-Resistant Staphylococcus aureus (MRSA) are pathogenic bacteria that play a significant role in antibiotic resistance. The discovery of effective and safe natural remedies ... -
Skrining Virtual In Silico dan Uji In Vitro Senyawa Inhibitor Multi Target CHK1, CHK2, dan WEE1 yang Berpotensi sebagai Kandidat Obat Anti Kanker
(Universitas Sumatera Utara, 2024)Breast cancer and ovarian cancer are cancers with the highest prevalence and mortality rates in women worldwide. CHK1, CHK2, and WEE1 are molecular pathways involved in many cancer cases. Inhibition of CHK1, CHK2, and ... -
Formulasi dan Uji Efek Antidiabetes Nanoliposom Ekstrak Buah Terung Bulat Hijau (Solanum xanthocarpum Schrader & Wendland) pada Tikus Jantan
(Universitas Sumatera Utara, 2024)Drug delivery systems can affect the effects of drugs in the body. One of the most rapidly used drug delivery systems is the nanoliposome form. This form can be applied in various drug dosage forms, both modern medicines ... -
Uji Aktivitas Antibakteri Daun Jahe Merah (Zingiber Officinale Rosc. Var. Rubrum) dan Sediaan Gel dari Fraksi Aktif sebagai Antiinflamasi terhadap Luka Eksisi yang Diinfeksi oleh Bakteri Uji
(Universitas Sumatera Utara, 2024)Background: Red ginger leaves are a natural material empirically used by communities to treat wounds. The leaves contain flavonoid compounds such as quercetin, luteolin, and resveratrol, which possess wound-healing ... -
Pengaruh Intervensi Digital Pengingat Minum Obat terhadap Kepatuhan Minum Obat dan Outcome Klinis pada Pasien Diabetes Melitus Tipe 2
(Universitas Sumatera Utara, 2025)Many researchs showed that the medication adherence is low in type 2 diabetes mellitus patients, so interventions are needed to increase compliance. One of these interventions is a medication reminder application. This ... -
Kajian Mekanisme Efek Gastroprotektif Ekstrak Etanol Daun Sukun (Artocarpus altilis (Parkinson) Fosberg) pada Tukak Lambung Tikus yang Diinduksi dengan Pyloric Ligation dan Mucosal Damage
(Universitas Sumatera Utara, 2024)Breadfruit (Artocarpus altilis) is a plant that is widespread in Indonesia and has the potential to prevent gastric ulcers. Breadfruit contains flavonoids and has anti-inflammatory, antibacterial, cytoprotective, and wound ... -
Formulasi Etosom Ekstrak Etanol Daun Tekelan (Chromolaena odorata L.) dan Karakterisasi Fisik, Uji Stabilitas Fisik, Penetrasi serta Aktivitas Antipenuaan Kulit secara In Vivo
(Universitas Sumatera Utara, 2024)Ethanol extract of tekelan leaves (Chromolaena ododrata L.) has secondary metabolites in the form of tannins, phenols, flavonoids, saponins, alkaloids, steroids and essential oils such as α-pinene, cadinene, champora, ... -
Penerapan Model Konseptual Telepharmacy Komunitas dalam Upaya Menerapkan Standar Pelayanan Kefarmasian
(Universitas Sumatera Utara, 2024)Community pharmacists, despite their business orientation, have an ethical responsibility to patients to ensure that they receive appropriate therapy. The pharmacist's professional duty to prevent medication errors and ... -
Kajian Efek Imunomodulator Ekstrak Etanolherba Binara (Artemisia vulgaris L.) secara In Vitro dan In Vivo
(Universitas Sumatera Utara, 2023)Herbs from the Binara plant (Artemisia vulgaris L.) are potentially medicinal herbs from Tanah Karo, North Sumatra which have been used traditionally to overcome skin infections and hypertension. Secondary metabolites and ... -
Eksplorasi Senyawa Antibakteri dari Bakteri Simbion Spons terhadap Bakteri Patogen
(Universitas Sumatera Utara, 2023)Background:Theproblem of infectious diseasesis increasing every year,oneofthe causesis that bacteriaareresistant to certain antibotics.An alternativesearchforsources of new activecompoundsis to usebacteria that arein ... -
Pengaruh Pemberian Ekstrak Etanol Daun Tapak Liman (Elephantopus scaber L.) terhadap Kualitas Daging, Fisiologi dan Performa Broiler
(Universitas Sumatera Utara, 2023)The increasing human population demands the availability of animal protein. Broiler is a source of animal protein that grows fast and can be harvested in a relatively short time. Broiler productivity can be supported by ... -
Formulasi dan Evaluasi in Vitro-in Vivo Nanosuspensi Ketoprofen sebagai Antiinflamasi
(Universitas Sumatera Utara, 2023)Ketoprofen is a non-steroidal anti-inflammatory drug that is poorly soluble in water and its use orally has side effects such as local irritation to the stomach. Irritation is caused by direct contact of insoluble drug ... -
Aktivitas Antikanker Ekstrak Etanol dan Fraksi Daun Ekor Naga (Rhaphidophora pinnata (L-f). Schott) terhadap Set MCF-7 dan Isolasi Senyawa Kimia Aktif sebagai Antikanker
(Universitas Sumatera Utara, 2014)Indonesia is rich in medicinal plants, one of which that was believed to be effective against cancer is “ekor naga” leaf (Rhaphidophora pinnata (L.f)Schott). The boiled “ekor naga” was traditionally used for the treatment ... -
Aktivitas Antioksidan dan Antikanker Ekstrak Daun Bangun-Bangun (Plectranthus amboinicus (Lour.) Spreng.) terhadap Kanker Payudara secara In Vitro dan In Vivo
(Universitas Sumatera Utara, 2014)The leaves of Plectranthus amboinicus, (Lour.) Spreng. of the family Lamiaceae, commonly called “bangun-bangun” in Indonesia has antioxidant property which can delay or inhibit oxidation so that prevent the cell damage ... -
Isolasi dan Karakterisasi Hemiselulosa dari Tongkol Jagung serta Uji Daya Ikat terhadap Kadmium dan Timbal Secara In Vitro dan In Vivo
(Universitas Sumatera Utara, 2012)Hemicellulose is a component of Non-Starch Polysaccarides(NSP) contained in agricultural byproduct and can be separated from the other components of NSP by isolation or hydrolysis. Various studies about hemicelluloses ... -
lsolasi dan Penentuan Struktur Senyawa Antimikroba dari Ekstrak n-heksana Talus Sargassum cinerium J.G.Agardh dari Pulau Mursalah Tapanuli Tengah
(Universitas Sumatera Utara, 2013)Sargassum cenerium J.G. Agardh yang digunakan sebagai bahan penelitian ini diambil dari pulau Mursalah yang terdapat di pantai perairan Sibolga. Tujuan dari penelitian ini adalah melakukan karakterisasi untuk mengetahui/ciri-ciri ... -
Dampak Konseling Farmasis terhadap Hasil Klinis Penatalaksanaan Diabetes Melitus Tipe 2 pada Pasien Rawat Jalan RSUD Cut Meutia Aceh Utara
(Universitas Sumatera Utara, 2011)Diabetes mellitus type 2 is a chronic disease which does directly not cause death although it is potentially deadly if it is not handled correctly. The management of DM (diabetes mellitus) needs handling medicinal and non ... -
Pembuatan Sediaan Gastroretentif Ranitidin Hidroklorida sebagai Antiulkus Menggunakan Polimer Alginat-Kitosan
(Universitas Sumatera Utara, 2015)Ranitidine HCl is absorbed in stomach and the initial part of the small intestine, and has short biological half life and poor bioavailability, hence, the treatment of gastric ulcus with ranitidine HCl conventional dosage ... -
Evaluasi Efek Fraksi N-Heksan, Etil Asetat dan Etanol Daun Puguntano (Picria Felterrae Lour.) terhadap Sistem Kardiovaskuler Tikus
(Universitas Sumatera Utara, 2016)Picria felterrae Lour (Schropulareaceae) is widely used in traditional medicine and reported to have activities as analgetic, antiinflamatory, antidiabetic, and antioxidant. The objective of this study was to evaluate ... -
Karakterisasi Ekstrak n-Heksana, Ekstrak Etilasetat, Ekstrak Etanol Daun Poguntano(Picria fel-terrae Lour) yang Berkhasiat Antidiabetes pada Mencit dan Elusidasi Struktur Salah Satu Kandungan Kimianya
(Universitas Sumatera Utara, 2014)Poguntano (Picria fel-terrae Lour) is a species of Scrophulariaceae, has been used to treat diabetes mellitus traditionally and give satisfactory results. The Research was intended to know antidiabetic activity of crude ...