Perbedaan Tingkat Disabilitas dan Kualitas Tidur Antara Wanita Premenopause, Perimenopause, dan Postmenopause yang Menderita Migren

Abstract

ABSTRACT Background: Changes in menstrual status have many implications in the lives of women as previous studies have shown that there is a link between hormonal changes and climacteric symptoms associated with the severity of migraine and sleep deprivation, especially during the transition to menopause. Objective: To find out the difference in the level of disability and sleep quality between premenopausal, perimenopausal, and postmenopausal women who suffer from migraines. Method: This cross sectional study included 36 women with migraine who were divided into 3 groups, namely premenopause, perimenopause, and postmenopause with a total of 12 subjects per group. Then the disability level was assessed using MIDAS (Migraine Dissability Assessment Scale) and sleep quality using PSQI (Pittsburgh Sleep Quality Index). Result: There was a significant difference in the level of disability between the premenopausal and perimenopausal groups (p = 0.005), between the premenopausal and postmenopausal groups (p = 0.034), but there were no significant disability differences between the perimenopausal and postmenopausal groups (p = 0.484). There was no significant difference in sleep quality between the premenopausal and perimenopausal groups (p = 0.059), between the premenopausal and postmenopausal groups (p = 0.386), and between the perimenopausal and postmenopausal groups (p = 0.284) Conclusion: Differences in menstrual status in women with migraine provide a significant difference in the level of disability especially in the premenopausal period when compared with the perimenopause and postmenopause period.

ABSTRAK Latar Belakang: Perubahan status menstrual membawa banyak implikasi pada kehidupan perempuan dimana penelitian-penelitian terdahulu menyebutkan adanya hubungan antara perubahan kadar hormonal dan gejala-gejala menopause yang menyertainya dengan timbulnya migren dan gangguan tidur terutama pada masa-masa transisi menuju menopause. Tujuan: Untuk mengetahui perbedaan tingkat disabilitas dan kualitas tidur antara perempuan premenopause, perimenopause, dan postmenopause yang menderita migren. Metode: Penelitian cross sectional ini mengikutsertakan 36 orang perempuan penderita migren yang dibagi menjadi 3 kelompok yaitu premenopause, perimenopause, dan postmenopause dengan jumlah subjek 12 orang tiap kelompok. Lalu dilakukan penilaian tingkat disabilitas mengunakan MIDAS (Migraine Dissability Assessment Scale) dan kualitas tidur dengan mengunakan PSQI (Pittsburgh Sleep Quality Index). Hasil: Terdapat perbedaan tingkat disabilitas yang bermakna antara kelompok premenopause dan perimenopause (p=0,005), antara kelompok premenopause dan postmenopause (p=0,034), namun terdapat perbedaan tingkat disabilitas yang tidak bermakna antara kelompok perimenopause dan postmenopause (p=0,484). Terdapat perbedaan kualitas tidur yang tidak bermakna antara kelompok premenopause dan perimenopause (p=0,059), antara kelompok premenopause dan postmenopause (p=0,386), dan antara kelompok perimenopause dan postmenopause (p=0,284) Kesimpulan: Perbedaan status menstrual pada perempuan penderita migren memberikan perbedaan yang bermakna terhadap tingkat disabilitas terutama pada periode premenopause bila dibandingkan dengan periode perimenopause dan postmenopause.