Luaran Kanker Ovarium Berdasarkan Modifikasi Glasgow Prognostik Skor

Abstract

Objective: To assess the relationship of mGPS score against ovarian cancer patient outcomes after surgery. The outcomes of patients assessed with the stage of ovarian cancer, optimal or suboptimal operation procedure and histopathology grading. Methods: This study was designed as a descriptive study with case series approach in ovarian cancer patient and analyzed by assessing the relationship. The study pperformed at RSUP H. Adam Malik, RSUD dr.Pirngadi and satelite hospital. The began in March 2015 untill June 2015. Sample collection by consecutive sampling. 26 patients with ovarian tumors that have examined the Hs-CRP level and albumin level, then underwent laparotomy surgical staging with histopathological results epithelial ovarian cancer. mGPS Score 0: CRP ≤ 10mg / L and albumin ≥35 g / L, Score 0: CRP ≤10 mg / L, and albumin <35 g / L, Score 1: CRP> 10mg / L, Score 2: CRP> 10mg / L and albumin <35 g / L. Data were analyzed computerized to assessing the relationship between mGPS scores and ovarian cancer stage, optimal or suboptimal operation procedure and histopathological staging. .Results: 26 ovarian cancer patients recruited in this study, the mean hsCRP level is 41.45 mg / L, and the mean albumin level is 35.31 g / dL. We found a relationship between the scores mGPS and (p 0.001) Conclusion: there is a relationship between the mGPS scores and histopathology grading in ovarian cancer patient.

Tujuan penelitian: Untuk menilai hubungan skor mGPS terhadap luaran pasien kanker ovarium setelah operasi. Luaran pasien dinilai dengan stadium kanker ovarium, keberhasilan operasi dan derajat histopatologi Desain penelitian: Penelitian ini dirancang sebagai penelitian deskriptif dengan pendekatan case series pada kasus kanker ovarium dan dianalisa dengan menilai hubungan.Penelitian ini dilakukan di RSUP H. Adam Malik, RSUD dr.Pirngadi dan Rumah sakit Jejaring. Waktu penelitian selama Maret 2015 - Juni 2015. Pengumpulan sampel dilakukan dengan cara consecutive sampling. Materi dan metode: 26 penderita tumor ovarium yang telah diperiksa nilai Hs-CRP dan nilai albuminnya kemudian menjalani laparatomi surgical staging dengan hasil histopatologi kanker ovarium jenis epitel. Dinilai skor mGPS nya. Skor 0: CRP ≤ 10mg/L dan albumin ≥35 g/L, Skor 0: CRP ≤10 mg/L dan albumin <35 g/L, Skor 1: CRP > 10mg/L, Skor 2: CRP > 10mg/L dan albumin <35 g/L. Skor mGPS ini kemudian dinilai sesuai dengan stadium, keberhasilan operasi dan derajat histopatologi pasien. Data dianalisa secara komputerisasi dan ditampilkan dalam diagram distribusi frekuensi, kemudian dianalisa dengan menilai hubungan. Hasil: Dari 26 penderita kanker ovarium yang ikut dalam penelitian ini didapatkan nilai mean HsCRP 41,45 mg/L, dan nilai mean albumin 35,31 g/dL. Dijumpai hubungan antara skor mGPS dan derajat histopatologi (p 0,001). Kesimpulan: terdapat hubungan antara nilai mGPS dengan derajat histopatologi kanker ovarium.