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    Hubungan Rasio Trombosit Limfosit dengan Penyempitan Pembuluh Darah pada Penyakit Jantung Koroner

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    Fulltext (1.640Mb)
    Date
    2016
    Author
    Marziah, Enny
    Advisor(s)
    Aman, Adi Koesoema
    Ketaren, Andre Pasha
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    Abstract
    Background: One of the diseases of the cardiovascular system that is most common is coronary artery disease (CAD), which is characterized by atherosclerotic lesions. Atherosclerotic vascular processes occur based multifactorial. One of them is the process of inflammation. Platelet/Lymphocytes Ratio (PLR) are markers that predict coronary atherosclerotic burden. This research report is to determine the association between platelet lymphocyte ratio and narrowed coronary arteries in patients with CAD. Material and methods: This research is an analytical observation with cross sectional design, conducted in 54 patients with CAD who underwent angiography in Haji Adam Malik Hospital, Medan in February–October 2016. Complete blood count was tested. Results: There is a weak correlation between platelet and lymphocyte ratio in CAD patients with narrowed coronary arteries (r = 0.225). Statistical test result found no significant association between platelet and lymphocyte ratio in CAD patients with narrowed coronary arteries (p=0.187). Conclusion: In this study there was poor association between platelet and lymphocyte ratio in CAD patients with narrowed coronary arteries.
     
    Latar belakang: Salah satu penyakit sistem kardiovaskuler yang paling sering terjadi adalah penyakit jantung koroner (PJK), yang ditandai dengan lesi aterosklerotik. Proses aterosklerosis pembuluh darah terjadi berdasarkan multifaktorial. Salah satunya yaitu adanya proses peradangan. Rasio trombosit limfosit (RTL) merupakan penanda yang memprediksi beban aterosklerotik koroner. Penelitian bertujuan untuk mengetahui hubungan antara rasio trombosit limfosit dan penyempitan arteri koroner pada pasien penyakit jantung koroner. Bahan dan Metode : Penelitian ini bersifat analitik observasional dengan rancangan penelitian potong lintang, yang dilakukan pada 54 pasien PJK yang menjalani angiografi Hasil Penelitian: Terdapat hubungan lemah antara rasio trombosit limfosit dan penyempitan arteri koroner pada pasien PJK dengan nilai r= 0, 276. Hasil uji statistik didapatkan hubungan yang signifikan antara rasio trombosit limfosit dan penyempitan arteri koroner pada pasien PJK (p=0,043).

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    http://repositori.usu.ac.id/handle/123456789/37301
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    Repositori Institusi Universitas Sumatera Utara (RI-USU)
    Universitas Sumatera Utara | Perpustakaan | Resource Guide | Katalog Perpustakaan
    DSpace software copyright © 2002-2016  DuraSpace
    Contact Us | Send Feedback
    Theme by 
    Atmire NV