Ko-Insidensi Covid-19 pada Pasien Kanker di RSUP H. Adam Malik dan RS USU Medan

Abstract

Background: The incidence of COVID-19 is at risk in patients with comorbid hypertension and diabetes mellitus, male sex, and active smokers. Cancer is associated with immunosuppressive reactions, cytokine overload, suppression of proinflammatory agent induction, and impaired dendritic cell maturation. Based on another study at a hospital in Wuhan, it was found that cancer patients from the epicenter of the viral epidemic had a higher risk of being infected with SARS-CoV-2. Based on the Based on the description above, the researchers wanted to know the co-incidence of COVID-19 in cancer patients at H. Adam Malik Hospital and USU Hospital Medan. Methods: This study is a descriptive study to assess the co-incidence of COVID-19 in cancer patients at H. Adam Malik Hospital and USU Hospital Medan. The sample of this study were all cancer patients at H. Adam Malik Hospital and USU Hospital Medan who met the inclusion criteria. Data classified into categories or code to make it easier to tabulate data. All data is processed and dieeplayed in a frequency distribution table with the help of statistical software. Results: It was found that from 891 patients, the average age of COVID-19 patients with cancer was 44 years while 12 patients (1.34%) experienced COVID-19 and Cancer Coincidence. The most cases were breast cancer patients with 3 cases. Conclusion: It was found that 12 patients (1.34%) had COVID-19 and cancer with the most cases were breast cancer, 3 cases and most of them have COVID-19 moderate degree.

Latar Belakang: Angka kejadian COVID-19 berisiko pada penderita komorbid hipertensi dan diabetes melitus, berjenis kelamin laki-laki, dan perokok aktif. Kanker dikaitkan dengan reaksi imunosupresif, kelebihan sitokin, penekanan induksi agen proinflamasi, dan gangguan pematangan sel dendritik. Berdasarkan penelitian lain di sebuah rumah sakit di Wuhan, ditemukan bahwa pasien kanker dari episentrum epidemi virus memiliki risiko lebih tinggi terinfeksi SARS-CoV-2. Berdasarkan uraian di atas, peneliti ingin mengetahui co-insiden COVID-19 pada pasien kanker di RS H. Adam Malik dan RS USU Medan. Metode: Penelitian ini merupakan penelitian deskriptif untuk menilai ko-insiden COVID-19 pada pasien kanker di RS H. Adam Malik dan RS USU Medan. Sampel penelitian ini adalah seluruh pasien kanker di RS H. Adam Malik dan RS USU Medan yang memenuhi kriteria inklusi. Data diklasifikasikan ke dalam kategori atau kode untuk memudahkan tabulasi data. Semua data diproses dan ditampilkan dalam tabel distribusi frekuensi dengan bantuan perangkat statistik. Hasil: Didapatkan dari 891 pasien, rata-rata usia pasien COVID-19 penderita kanker adalah 44 tahun sedangkan 12 pasien (1,34%) mengalami COVID-19 dan Cancer Coincidence. Kasus terbanyak adalah pasien kanker payudara dengan 3 kasus. Kesimpulan: Ditemukan 12 pasien (1,34%) menderita COVID-19 dan kanker dengan kasus terbanyak adalah kanker payudara, 3 kasus dan sebagian besar menderita COVID-19 derajat sedang.