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    Aktivitas Antimikroba Herba Meniran (Phyllanthus niruri L.) terhadap Bakteri dan Khamir Patogen

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    Date
    2011
    Author
    Desfita, Vivi
    Advisor(s)
    Suryanto, Dwi
    Munir, Erman
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    Abstract
    The aim of this study was to investigate the antimicrobial activity of meniran (Phyllanthus niruri L.) on pathogenic bacteria and yeast. The meniran was extracted with several solvent, such as n-hexane, etyl acetate, and methanol. The result of this study showed that the extracts inhibitated the growth of pathogenic bacteria Staphylococcus aureus and Eschericia coli, and yeast Candida albicans to some extent. The optimal antimicrobial activity was obtained from methanol extract. The high concentration showed inhibition zone accordingly. The extract showed cytotoxic activity with the value of LC50 < 1000 μg/ml. The chemical compound analysis showed that extract of meniran contains alkaloid, glicoside, steroid and free triterpene, saponin, tannin, and flavonoid.
     
    Penelitian ini bertujuan untuk menguji aktivitas antimikroba herba meniran (Phyllanthus niruri L.) terhadap bakteri dan khamir patogen. Herba meniran diekstrak dengan pelarut yang berbeda yaitu n-heksana, etil asetat, dan metanol. Hasil penelitian menunjukkan ekstrak herba meniran dapat menghambat pertumbuhan bakteri patogen Staphylococcus aureus dan Eschericia coli serta khamir patogen Candida albicans dengan besar zona penghambatan yang berbeda. Ekstrak yang memiliki aktivitas antimikroba optimal dihasilkan dengan menggunakan pelarut metanol. Semakin besar konsentrasinya semakin besar pula aktivitas antimikrobanya. Ekstrak herba meniran memiliki aktivitas sitotoksik dengan nilai LC50 < 1000 μg/ml. Analisis senyawa kimia menunjukkan dalam ekstrak herba meniran mengandung alkaloida, glikosida, steroida dan triterpen bentuk bebas, saponin, tanin dan flavonoida.

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    http://repositori.usu.ac.id/handle/123456789/41235
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    Repositori Institusi Universitas Sumatera Utara (RI-USU)
    Universitas Sumatera Utara | Perpustakaan | Resource Guide | Katalog Perpustakaan
    DSpace software copyright © 2002-2016  DuraSpace
    Contact Us | Send Feedback
    Theme by 
    Atmire NV