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    Faktor risiko kejadian tuberkulosis laten pada anak kontak serumah dengan tuberkulosis dewasa

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    Date
    2014
    Author
    Panjaitan, Flora Mindo
    Advisor(s)
    M. Daulay, Ridwan
    Supriatmo
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    Abstract
    Background Tuberculosis (TB) is highly prevalent in Indonesia, and children carry a large proportion of the overall burden. Early detection of latent TB in children is an important strategy to control TB. Objective To determine the risk factor of latent TB in children (3 months – 18 years) with household contact to adult TB patients. Methods A cross sectional study was conducted between February to March 2014 in Medan. We studied children aged 3 months to 18 years old living in the same house with adult TB patients. The association of the risk factor and the occurrence of latent TB were analyzed by using chi square and fisher’s exact test. The risk factor that may associate to the occurrence latent TB were analyzed by using multivariate logistic regression. Results Of the 48 children, we obtained 19 (39.6%) latent TB. Bivariate analysis showed the BCG immunization status, the economic status, house ventilation and residential density have a significant association with the occurrence of latent TB in children with households contact to adult TB patients with OR 0.06, 8.59, 6.60 and 9.63, respectively. After multivariate logistic analysis, the BCG immunization status has a significant association with the occurrence of latent TB in children with households contact to adult TB patients (OR 0.02). Conclusion The BCG immunization status is a protective factor to the occurrence of latent TB in children with households contact to adult TB patients.
     
    Latar belakang Prevalensi tuberkulosis (TB) adalah tinggi di Indonesia, dan TB anak mengambil proporsi besar dari keseluruhan beban TB. Deteksi dini terhadap TB laten pada anak merupakan strategi penting untuk mengkontrol TB. Tujuan Untuk menentukan faktor risiko TB laten pada anak (3 bulan – 18 tahun) kontak serumah dengan penderita TB dewasa. Metode Sebuah studi potong lintang dilakukan pada Februari - Maret 2014 di Medan. Sampel adalah anah umur 3 bulan – 18 tahun kontak serumah dengan penderita TB dewasa. Hubungan antara faktor risiko dan kejadian TB laten dianalisa dengan menggunakan chi square dan tes fisher’s exact. Faktor risiko yang diduga berhubungan dengan TB laten dianalisa dengan menggunakan analisis multivariat regresi logistik. Hasil Dari 48 anak didapati TB laten sebanyak 19 (39.6%). Analisis bivariat menunjukkan status BCG, status ekonomi, ventilasi rumah dan kepadatan penghuni rumah mempunyai hubungan bermakna dengan kejadian TB laten pada anak kontak serumah dengan penderita TB dewasa dengan masing – masing RO 0.06, 8.59, 6.60 dan 9.63. Setelah analisis multivariat, status BCG mempunyai hubungan bermakna dengan kejadian TB laten pada anak kontak serumah dengan TB dewasa (RO 0.02). Kesimpulan Status BCG merupakan faktor proteksi terhadap kejadian TB laten pada anak kontak serumah dengan TB laten.

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    http://repositori.usu.ac.id/handle/123456789/43012
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    Repositori Institusi Universitas Sumatera Utara (RI-USU)
    Universitas Sumatera Utara | Perpustakaan | Resource Guide | Katalog Perpustakaan
    DSpace software copyright © 2002-2016  DuraSpace
    Contact Us | Send Feedback
    Theme by 
    Atmire NV