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    Uji Efektivitas Gel Limbah Degumming Kokon Ulat Sutera (Bombyx mori L.) terhadap Perbaikan Pigmentasi Kulit

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    Date
    2021
    Author
    Jannah, Raudhatul
    Advisor(s)
    Tanjung, Masitta
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    Abstract
    Limbah degumming kokon ulat sutera mengandung asam amino berupa serisin dan fibroin yang berpotensi dalam pemulihan kulit yang terpapar radiasi ultarviolet. Penelitian ini bertujuan untuk mengetahui keefektifan dari penggunaan gel limbah degumming kokon ulat sutera terhadap pemulihan kulit yang terpapar sinar ultraviolet dan mengetahui nilai Sun Protection Factor (SPF). Rancangan penelitian yang dilakukan adalah metode Rancangan Acak Lengkap (RAL) yang terdiri dari 5 kelompok perlakuan yaitu pemberian tabir surya komersil yang mengandung bahan aktif Avobenzone, kelompok tanpa pemberian sediaan tabir surya, serta pemberian gel limbah degumming kokon ulat sutera dengan tiga tingkatan konsentrasi yaitu 20%, 40%, dan 60% selama 14 hari. Penelitian ini menggunakan hewan uji tikus putih (Rattus norvegicus) jantan sebanyak 25 ekor, usia 6-8 minggu. Pengamatan yang dilakukan adalah morfologi secara visual dan histologi. Pembuatan preparat organ kulit menggunakan metode parafin, dengan pewarnaan Hematoksilin-Eosin (HE). Hasil penelitian menunjukkan gel limbah degumming kokon ulat sutera memiliki nilai SPF yang cukup tinggi dengan kategori perlindungan ekstra sebesar 7,10 pada konsentrasi 60%. Pada pengamatan morfologi juga menunjukkan dapat berpotensi dalam mempercepat pemulihan kondisi kulit yang ditandai dengan kulit lembab, tidak adanya kerutan serta kemerahan. Terjadi peningkatan ketebalan jaringan epitel hingga batas normal, serta diikuti penurunan jumlah sel melanosit (p0,05). Semakin tinggi konsentrasi limbah degumming kokon ulat sutera, maka semakin berpotensi dalam proses pemulihan kulit yang terpapar sinar ultraviolet.
     
    Waste degumming cocoon of silkworm contains amino acids sericin and fibroin which have potential to restore skin damaged exsposed by ultraviolet light. This research aims to find out the effect of silkworm cocoon degumming gel recovery of skin exsposed by ultraviolet light and the value of Sun Protection Factor (SPF). The research used Completely Randomized Design (CRD) which consisted of 5 treatment groups, namely administration of commercials sunscreens containing the active ingredient avobenzone, the group without the administration of sunscreen preparation and the administration of silkworm cocoon degumming waste gel with three levels of concentration namely 20%, 40%, 60% for 14 days. The research used a test animal 25 male rats (Rattus norvegicus). The observation made were visual morphology and histology. Preparation of skin organ preparations using the paraffin method with Hematoxylin-Eosin (HE) staining. The results showed that the silkworm cocoon degumming waste gel had a fairly high SPF value with an extra protection category of 7,10 at a concentration 60%. Morphologycal observation also show that it has the potential to accelerate the recovery of skin condition which are caracterized by most skin, no wrinkles, and redness. There was an increase in epithellial thickness and a decrease in melanocyte cells (p0,05). The higher the concentration of silkworm cocoon degumming waste, was followed by the recovery proccess of skinn exposed by ultraviolet light.

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    https://repositori.usu.ac.id/handle/123456789/44746
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    Repositori Institusi Universitas Sumatera Utara - 2025

    Universitas Sumatera Utara

    Perpustakaan

    Resource Guide

    Katalog Perpustakaan

    Journal Elektronik Berlangganan

    Buku Elektronik Berlangganan

    • Perpustakaan
    • Resouce Guide
    • Katalog Perpustakaan
    DSpace software copyright © 2002-2016  DuraSpace
    Contact Us | Send Feedback
    Theme by 
    Atmire NV