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    Hubungan Neutrophil Lymphocyte Ratio pada Anak dengan Gastritis H. Pylori dan Non H. Pylori

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    Fulltext (2.803Mb)
    Date
    2021
    Author
    Deyuga, M. Riza
    Advisor(s)
    Supriatmo
    Lubis, Aridamuriany D
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    Abstract
    Background: Helicobacter pylori infection occurs in about 50% of the world's population and most infections occur in childhood. This infection involves local inflammation in the stomach and a systemic humoral immune response that causes an increase in neutrophils and a decrease in the number of lymphocytes. Objective: This study aims to determine the relationship between the value of Neutrophil Lymphocyte Ratio in children with H. pylori infection and non H. pylori infection. Methods: This cross-sectional analytic study involved 96 children aged 2-18 years who met the research criteria, their blood was taken and HPSA examination was performed, followed by bivariate analysis using the chi square test. Results: The results showed that the research subjects at the age of 11.66 ± 3.69 years, mostly female (63.5%), with 51 children (53.1%) positive for H. pylori infection. Conclusion: There was no significant relationship between the ratio of neutrophil lymphocytes and H. pylori infection (p = 0.509).
     
    Latar Belakang: Infeksi Helicobacter pylori terjadi pada sekitar 50% populasi dunia dan sebagian besar infeksi terjadi selama masa kanak-kanak. Infeksi ini melibatkan peradangan lokal di lambung dan respon imun humoral sistemik sehinga menyebabkan peningkatan jumlah neutrofil dan penurunan jumlah limfosit. Tujuan: Penelitian ini bertujuan untuk mengetahui hubungan antara nilai Neutrophil Lymphocyte Ratio pada anak dengan infeksi H. pylori dan non H. pylori. Metode: Penelitian analitik secara cross sectional ini melbatkan 96 anak-anak usia 2-18 tahun yang memenuhi kriteria penelitian diambil darah dan dilakukan pemeriksaan HpSA, dilanjutkan dengan analisis bivariat menggunakan uji chi square. Hasil: Hasil penelitian menunjukkan subjek penelitian berusia 11,66 tahun ± 3,69 tahun, sebagian besar berjenis kelamin perempuan (63,5%), dengan 51 anak-anak (53,1%) dijumpai positif terinfeksi H. pylori. Kesimpulan: Tidak ditemukan hubungan yang signifikan antara rasio neutrofil limfosit dengan infeksi H. pylori (p = 0,509).

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    https://repositori.usu.ac.id/handle/123456789/47419
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    Repositori Institusi Universitas Sumatera Utara (RI-USU)
    Universitas Sumatera Utara | Perpustakaan | Resource Guide | Katalog Perpustakaan
    DSpace software copyright © 2002-2016  DuraSpace
    Contact Us | Send Feedback
    Theme by 
    Atmire NV