Faktor-faktor Prediktor Hasil Pengobatan Pasien Covid-19 di Rumah Sakit Haji Adam Malik Medan

Abstract

Background: Coronavirus Disease 2019 (COVID-19) is an infectious disease caused by Severe Acute Respiratory Syndrome Coronavirus-2 (SARSCoV-2). Coronavirus disease 2019 (COVID-19) has become a worldwide pandemic. This study aims to determine what are the predictor factors for the prognosis of COVID-19 patients at Haji Adam Malik General Hospital, Medan.. Methods: This study is a descriptive study with a cross sectional design carried out on the medical records of 110 inpatients with positive RT PCR results for COVID-19 who were hospitalized from December 2020 to April 2021. The inclusion criteria for case samples from this study were patients diagnosed with COVID-19 based on RT-PCR test and exclusion criteria incomplete medical records. Characteristic analysis was performed by Kruskal Wallis, comorbid analysis by Kolmogorov-Smirnov and analysis of outcome using chi-square. Results: Male sex suffers more from COVID-19 than female. There was a relationship between age, lymphocyte values, N/L ratio, CRP, procalcitonin, D-dimer, fibrinogen, ferritin and the degree of COVID-19 disease at the time of hospitalization. There was a relationship between the presence of comorbid Diabetes mellitus, hypertension, HIV, heart disease, kidney disease, and the degree of Covid-19 disease at the time of hospitalization. There was a relationship between age, comorbid hypertension, heart disease, kidney disease, cancer and degree of severity with treatment outcomes in COVID-19 patients. There was a relationship between laboratory results of lymphocyte values, N/L ratio, and D-dimer with outcomes in COVID-19 patients. Conclusion: The predictor factors of COVID-19 at HAM Hospital include age, lymphocytes, N/L ratio, D-dimer, comorbid hypertension, heart disease, kidney disease, cancer and degree of severity.

Latar Belakang: Coronavirus Disease 2019 (COVID-19) adalah penyakit menular yang disebabkan oleh Severe Acute Respiratory Syndrome Coronavirus-2 (SARSCoV-2). Coronavirus disease 2019 (COVID-19) telah menjadi pandemi di dunia. Penelitian ini bertujuan untuk mengetahui faktor faktor prediktor hasil pengobatan pasien COVID-19 di RSUP Haji Adam Malik Medan. Metode: Penelitian ini merupakan penelitian deskriptif dengan design cross sectional dilakukan pada rekam medis 110 pasien rawat inap dengan hasil RT PCR COVID-19 positif yang dirawat inap dari bulan Desember 2020 samapi April 2021. Kriteria inklusi sampel kasus dari penelitian ini pasien yang terdiagnosis COVID-19 berdasarkan RT-PCR dan kriteria eksklusi sampel kasus yaitu rekam medis yang tidak lengkap. Analisis karakteristik dilakukan dengan Kruskal Wallis, analisis komorbid dengan Kolmogorov-Smirnov dan analisis hasil penelitian mengunakan chi-square. Hasil: Jenis kelamin laki-laki lebih banyak menderita COVID-19 daripada perempuan. Didapatkan hubungan antara usia, nilai limfosit, N/L rasio, CRP, prokalsitonin, D-dimer, fibrinogen, feritin dengan derajat penyakit covid-19 pada saat masuk rawat inap. Didapatkan hubungan antara adanya komormid diabetes melitus, hipertensi, HIV, penyakit jantung, penyakit ginjal, dengan derajat penyakit covid-19 pada saat masuk rawat inap. Didapatkan hubungan antara usia, komorbid hipertensi, penyakit jantung, penyakit ginjal, kanker dan derajat penyakit dengan hasil pengobatan pada pasien covid-19. Didapatkan hubungan antara hasil laboratorium nilai limfosit, N/L rasio, dan D-dimer dengan hasil pengobatan pada pasien covid-19. Kesimpulan: Faktor faktor prediktor COVID-19 di RSUP HAM antara lain usia, limfosit, N/L rasio, D-dimer, komorbid hipertensi, penyakit jantung, penyakit ginjal, kanker dan derajat penyakit.