Hubungan antara p53 dengan Derajat Histopatologi WHO pada Penderita Astrositoma Intrakranial di RSUP H. Adam Malik Medan

Abstract

Background: The degree of histological has been widely accepted as a marker of prognosis of patients with astrocytma one proliferation index. Astrocytoma differentiated into 4 degrees on the WHO classification. Difficulties often encountered when determining whether it is an astrocytoma astrocytoma grade 2 or level 3. Protein p53 is involved in a variety of malignancies, including brain tumors. P53 genetic changes generally occur in astrocytomas.