Hubungan Derajat Albuminuria dengan Beratnya Lesi Arteri Koroner pada Pasien Penyakit Jantung Koroner

Abstract

Introduction : Coronary heart disease (CHD) is currently one of the major health problems in the world. Corrective CHD is defined as the presence of minimal ≥ 50% stenosis in a single coronary artery evidenced by an angiographic examination. The degree of stenosis in the coronary artery can be seen by angiographic action and is usually measured by a visual evaluation of the presentation of the relative diameter reduction against the adjacent normal segment. At this time, it is known that microalbuminuria is a picture of a thorough and equitable process of endothelial damage glomelurus, retina and tunica intima large blood vessels. Aim : To determine the relationship of degree of albuminuria to the severity of coronary artery narrowing based on angiography examination in patients with CHD Methods : A total of 58 patients of CHD inpatient RSUP H. Adam Malik Medan who underwent angiography examination and has met the inclusion criteria.Dilakukan data collection of complete blood laboratory, troponin T, CKMB, mikroalbuminuria and angiography. Statistical analysis with chi square correlation test Results : Of the 58 subjects in which the subjects of normal grade microalbuminuroa (10,7%) macroalbuminuria (0%) while in grade 1 microalbuminuria (1%) macroalbuminuria (6.7%), grade 2 microalbuminuria (32.1%) macroalbuminuria (0%) And grade 2, 3 macroalbuminuria (46.7%). The result of chi square test showed that there was a significant correlation between microalbuminuria and degree of coronary artery lesion (p <0.001). Conclusion : With elevated levels of microalbuminuria will be followed increasing the degree of severity of coronary artery lesions. There was a significant correlation between microalbuminuria and degree of coronary artery lesion (p <0.001).