Efek Aminophylline Intravena untuk Mempercepat Waktu Pulih Sadar Pasca General Anestesi pada Pasien Pembedahan Laparatomi dengan Menggunakan Bispectral Index di RSUP Haji Adam Malik Medan

Abstract

Background : Surgery is an invasive medical treatment performed to diagnose or treat a disease, injury, or deformity of the body. Objective : To determine the effect of intravenous aminophylline to speed up recovery time afier postoperative general anesthesia in laparatomy surgery patients by using bispectral index at Haji Adam Malik Hospital, Medan. Methods : The research method used was a randomized and double-blind randomized controlled trial. This research was carried out at Haji Adam Malik General Hospital Medan from June to September 2018. The study population was all subjects who were electively scheduled to undergo abdominal laparotomy with general anesthesia technique with isoflurane inhalation at Haji Adam Malik General Hospital. The total sample obtained was 46 patients. The normal test of numerical data was used by fisher exact test. 111e research hypothesis was tested using the Mann-Whitney test. In the study conducted on 46 samples which were divided into 2 groups, it was found that there were significant differences between the two groups in the value of conscious recovery time in patients with general anesthesia. Results : Based on this study, the results is patients recovered consciously with aminophylline average 10.48 minutes were calculated starting from TO (when administering aminophylline) and with NaCl 0.9%, the average time of 15.48 minutes was calculated from TO (when administering aminophylline), which of the two drugs that are given aminophylline can accelerate conscious recovery time in patients with general anesthesia. In the results of this study it was found that the use of aminophylline gave a faster recovery time compared to 0.9% NaCl (p <0.05) by shortening the time to almost haft: compared to the average recovery time. Administration of 0.9% NaCl in patients with general anesthesia did not affect recovery time after general anesthesia was assessed using the bispectral index. Conclusion : Administration of aminophylline in patients with general anesthesia can speed up recovery time after general anesthesia is assessed using the bispectral index. Administration of aminophylline in patients with general anesthesia can accelerate recovery time afier general anesthesia compared with 0.9% NaCl which was assessed using the bispectral index.