| dc.description.abstract | Background : Stroke is a leading cause of death and long-term disability
worldwide that includes various pathophysiological entfties that include
thrombosis, hemorrhage and embolism. Diagnosis currently relies on the
stroke clinical examination the doctor and was further supplemented with
various neuroimaging techniques. There have been studies on employing
some laboratory markers besides advanced radiologic methods in differential
diagnosis of ischemic and hemorrhagic stroke. Homeostatic abnormalities
could be a result of brain injury more than primary activation of system during
acute phase of ischemic or hemorrhagic stroke.
Objective: To compare the levels of markers of coagulation in patients with
acute ischemic stroke and acute hemorrhagic stroke.
Methods : This study is a cross-sectional study conducted on patients who
seek treatment at the Department of Neurology H. Adam Malik Medan. All
subjects were examined levels of markers of coagulation such as D-dimer,
fibrinogen, aPTT, PT and JNR. Test results were analyzed by statistical
analysis using Chi-square.
Results : Of the 74 research subjects consisted of 37 subjects with acute
ischemic stroke patients and 37 people who had acute hemorrhagic stroke.
Male totaled 43 people (58.1%) and 31 women (41.9%). Average age of
subjects was 57,50±12,51 years old. All subjects did not differ in terms of
demographic characteristics. There were no differences in the levels of D-
dimer, fibrinogen, aPTT, PT and INR (respectively p = 0.480, p = 0.582, p =
0.888, p = 0.100, p = 0.982) were significant among patients with acute
ischemic stroke and acute hemorrhagic stroke.
Conclusion : There were no differences in levels of markers of coagulation
between acute ischemic stroke and acute hemorrhagic stroke. | en_US |
