Hubungan Infeksi Bakteri pada Dermatitis Atopik dengan Indeks Scoring Atopic Dermatitis

Abstract

Background. Children with atopic dermatitis (AD) are more susceptible to skin infections, and vice versa. Skin infection can trigger and aggravate atopic dermatitis. Objective. The objective of the study was two folds. First, the study was intended to determine the association between skin infection in atopic dermatitis with SCOring Atopic Dermatitis (SCORAD) index. Secondly, the study was also intended to identify microorganisms which often infect skin in atopic dermatitis. Methods. This study was a cross-sectional study of 80 children with atopic dermatitis who visited Helvetia and Padang Bulan Community Health Center, Medan from April to May 2016 for medical treatment. Subject characteristics were taken based on interview with their family. Index of SCORAD was used to evaluate the severity of AD, and skin lesion was smeared with cotton swabs to take sterile culture. Data were analysed using Chi square and Mann Whitney test with 95% CLP value <0.05 was considered statistically significant. Results. Total respondents in this study were 80 people, consisting of 47 females and 33 males. ·-· ···-- .. . -- . ·- . .. There were 50 respondents with atopic dermatitis suffered skin infection. The most common microorganism isolated from skin infection (mild, moderate, or severe) in atopic dermatitis was Staphylococcus aureus. The result showed there was a significant association between the classification SCORAD and bacterial infection in atopic dermatitis (p = 0.011) with 2.06 PR (95% CI= 1.17-3.63). Conclusion. There is a relationship between bacterial infection in atopic dermatitis with SCORAD index, where atopic dermatitis with bacterial infection had higher SCORAD index. In this study, Staphylococcus aureus is the most common cause of skin infections in atopic dermatitis.