| dc.description.abstract | Background: There is growing recognition that ischemic brain lesions
have significant contribution in cognitive impairment. We hypothesized that
specific size and location of brain lesion would associated with certain
aspects of cognitive function in stroke patients.
Purpose: The aim of this study was to assess the association of lesion
size and location with aspects cognitive function using Mini Mental State
Examination (MMSE) and Clock Drawing Test (CDT) in ischemic stroke
patients.
Method: This was a cross sectional study of 60 chronic ischemic stroke
patients who came to Haji Adam Malik General Hospital. The size and
location of brain infarction identified by Head CT scan. Cognitive function
were assessed by using MMSE and CDT.
Results: Of 60 patients, 34 were males (56. 7%) and 26 were females
(43.3%). The largest age group was 50-60 years old (33 subjects,
55.0%). The largest subject according to the size of lesion was 10-30 cm3
(36 subjects, 60,0%). The largest lesion location was in subcortex (32
subjects, 53,3%) and left hemisphere (25 subjects, 41,7%). The average
MMSE score was 20.48 ± 5.000. The average CDT value was 2.90 ±
0.933. There was a significant correlation between the size of the lesion
with cognitive aspects of registration, recall, language, visuospatial and
executive (p <0.05). There was a significant correlation between location
hemisphere lesion with deficite in registration, recall, attention and
calculation, visuospatial and executive (p <0.05).
Conc/ussion: From this study, we found that the size of lesion effect on
registration, recall, language, visuospatial and executive. The location of
hemispheric lesion cause more deficit in registration, recall, attention and
calculation, visuospatial and executive. | en_US |
