| dc.description.abstract | Background: Many studies show that low circulating 25(OH)D serum level
may increase risk of morbidity and mortality, especially in women and
vitamin D deficiency are considered new markers for metabolic disease-
Objective: The objective was to identify vitamin D status in women and
factors that association with 25(OH)D serum level, such as single
nucleotide polymorphism of vitamin D receptor gene (Taql and Bsml),
lifestyle, and body fat associated with 25(OH)D serum level in women.
Method: This was a cross-sectional study, we include 156 healthy women
with no other disease. We investigated by Taql and Esml single nucleotide
polymorphism, lifestyle (sunlight exposure, vitamin D intake, and physical
activity), and body fat. Blood tests was measurements of 25(OH)D serum
level.
Results: The mean (tSD) of 25(OH)D serum level was 18.8 t7.0 ng/ml,
for 148 subjects categorized in deficiency and insufficiency and 8 subjects
categorized in sufficiency. All the subjects have heterozygote (TC for Taql
and AG for Bsml). All subjects had lower sun exposure, vitamin D intake,
and physical activity. The body fat level was 31.9t5.4, logistic regression
showed association in body fat and vitamin D intake with 25(OH)D serum
level.
Conclusions: The results indicate that vitamin D deficiency can be found
in women, especially with unbalance lifestyle and higher body fat. lt also
showed polimorphism in vitamin D receptor gene | en_US |
