Perbandingan Nilai Rasio Neutrofil-Limfosit dan Kadar C-Reactive Protein pada Penderita Systemic Inflammatory Response Syndrome dengan Kultur Darah Positif dan Kultur Darah Negatif

Abstract

lntroduction:Systemic lnflammatory Response Syndrome (SlRSl is a nonspecffic reaction that could be caused by infection, inflammation, or a combination of both factors. Bacteremia detectian in S/RS patients is a

challenge for clinicians. Neutrophil-lymphocyte count ratio (NLCR) and C- reactive protein (CRP) could rapidly predict bacteremia.

Method:This is a cross sectional study that was conducted in RSUP.H.Adam Malik l\ledan Emergency Room from January 2016 to March 2016. Patients that met SIRS criteria had their NLCR, CRP and blood culture tested. ResultOf 48 samples,2l (43.75%) were male and 27 (56.25%) were female. ln this study, there was significant difference of NLCR from both groups, where NLCR in $lRS with positive blood culture was higher that SIRS with negative blood culture (38.16 x 34.97 vs 9.68 *, 5.26, P = A.001). And there was significant difference between CRP in both groups. CRP in SIRS with positive blood culture was higher than SIRS with negative blood culture. (5.89 t 3.09 vs 3.15 + 1.89, P = 0.001). Discussion:NlCR is a simple biomarker that can be used to detect the presence of systemic infections in critically ill patients, in this study there was a significant difference between NLCR and CRP in SIRS patients with positive and negative blood culture. Conclusions and Suggesstion:There is significant difference of NLCR and CRP ,n SIRS patients with positive and negative blood culture. RNL and CRP could be used as a marker for detecting bacteremia in SIRS patients