Pengaruh Intensitas Kebisingan terhadap Gambaran Histopatologis Lambung Tikus Putih (Rattus norvegicus L.) Jantan

Abstract

Noise is undesired sound which can affect and threaten one’s health. Objective of this study is to obtain histopathological image of Rattus novergicus L. stomach under effect of noises. This research was experimental design as Complete Randomized Design with four treatment groups and six replications. The four treatment groups were designated as control group (P0, less than 20dB), group one (P1, 25-50 dB), group two (P2, 55-80 dB), and group three (85-110dB) with noise given within eight hours daily for seven days continuously. Histology preparation was made using paraffin method and Eosin-Hematoxylin staining. The results of stomach morphological observation showed a color change but not for stomach consistency. The results of body mass observation showed that there was a significant differences (P<0,05) between P0 and P2 and between P2 and P3 while stomach weight observation didn’t give any significal differences (P<0,05). Histological image of stomach resulted in gastric ulcer or gastritis with serious erosion degree was found significantly different between P1 and P2.