dc.description.abstract | Exposure to noise that exceeded the ability of adaptation can lead to various
medical disorders, such as distress caused by stresses. Mangosteen peel extract
contains active compounds that have pharmacological activity which could lessen
the impact of distress. Number of leucocytes and leucocytes types are used to
determine whether there is or there isn’t medical disorders that are occurring in
the body. This study was an experimental study using complete randomized
design (CRD) with 6 treatment group and 5 replications. (P0) was a blank control,
(P1) was given control of mangosteen peel extract from the 1st day until 16 st day
and (P2) was given both control of noise from the 1st day until 16 st day and
distilled water. The next groups were given a mangosteen peel extract from the 1st
day until 16 st day and then given noise with different noise levels, namely: (P3)
25-50 dB, (P4) 55-80dB, (P5) 85-110 from 9 st day to 16 st day. The volume of
mangosteen peel extract was given is 0.5 ml /day/oral. The results showed an
increase in total number of leucocytes, lymphocytes and monocytes cell count but
decreased in neutrophils cell counts. The results of statistical tests showed there is
no significant differences from the amount of leucocytes, neutrophils, basophils,
lymphocytes and eosinophils cells count but significantly different in the number
of monocytes. | en_US |