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    Perbandingan Kadar Zinc Plasma pada Berbagai Derajat Keparahan Akne Vulgaris di RSUP H. Adam Malik Medan

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    Date
    2013
    Author
    S, T Sy Dessi Indah Sari A
    Advisor(s)
    Simanungkalit, Rointan
    Jusuf, Nelva Karmila
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    Abstract
    Background: Acne vulgaris is a cutaneous dissoder due to chronic infection of pilosebaceous follicle. The Etiopathophysiology of acne vulgaris are multifactorial, they are; hormonal, acnegenic/comedogenic cosmetics, stress, foods, genetic and mineral deficiency, such as zinc. Objectives: To analyse the differences of plasma zinc level in mild, moderate, severe acne vulgaris and control. Method: This is an analytic cross sectional study involving 30 acne vulgaris patients (10 patients for each mild, moderate, and severe acne vulgaris) and 30 healthy patients as control. Each subject had been examined and blood sample was taken to measure plasma zinc level. Statistic analysis for comparison had been analyzed by Anova test. Result: Significant differences of plasma zinc level was found between mild (26,74 μg/dl), moderate (23,033 μg/dl), severe (21.16 μg/dl) acne vulgaris and control (24,362 μg/dl).p-value =0,282. Conclusion: Significant differences of plasma zinc level was found between mild, moderate, severe acne vulgaris and control
     
    Latar belakang: Akne vulgaris adalah penyakit kulit yang terjadi akibat peradangan menahun folikel pilosebasea. Patofisiologi akne vulgaris adalah multifaktorial dengan faktor-faktor yang berkaitan adalah hormonal, kosmetika yang bersifat aknegenesis/komedogenesis, stres, makanan, genetik dan defisiensi mineral seperti zinc. Tujuan: Untuk mengetahui perbandingan kadar zinc plasma pada penderita akne vulgaris deraj at ringan, sedang, berat, dan indi vidu normal. Subyek dan metode: Pene1itian analitik dengan rancangan cross sectional yang melibatkan 30 orang penderita akne vulgaris (masing-masing 10 orang untuk akne vulgaris ringan, sedang dan berat) dan 30 orang kontrol sehat. Setiap subyek penelitian dilakukan pemeriksaan dermatologi dan diambil darah untuk mengukur kadar zinc, hasil kemudian dibandingkan dengan analisis statistik menggunakan uj i An ova. Hasil: Ditemukan perbedaan bermakna antara kadar zinc plasma kelompok akne vulgaris derajat ringan (26,74μg/dl), sedang (23,033 μg/dl), berat (21.16 μg/dl) dan kontrol (24,362 μg/dl) denganp- value=0,282. Kesimpulan : Terdapat perbedaan bermakna kadar zinc plasma penderita akne vulgaris derajat ringan, sedang, berat dan individu normal

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    https://repositori.usu.ac.id/handle/123456789/72676
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    • Master Theses [206]

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    Repositori Institusi Universitas Sumatera Utara (RI-USU)
    Universitas Sumatera Utara | Perpustakaan | Resource Guide | Katalog Perpustakaan
    DSpace software copyright © 2002-2016  DuraSpace
    Contact Us | Send Feedback
    Theme by 
    Atmire NV