| dc.description.abstract | Paracetamol (C8H9NO2) has characteristics that crystalline powder form, white,
odorless and taste slightly bitter. Paracetamol generally have effectiveness in
relieving pain, but paracetamol was not overly irritate the stomach and therapeutic
effects of anti-fever paracetamol higher. But it does not mean that paracetamol has
no side effect. There was toxic in the liver if use in large doses. Determination of
active matter in paracetamol tablets 500 mg using High Performance Liquid
Chromatography (HPLC) method by using detector UV-Vis with wave length 243
nm was done. From data was obtained the content of active matter paracetamol that
was 101,004% and 101,029%, it means that active matter in paracetamol tablets to
comply requirement according to Farmakope Indonesia Edition IV that was not less
than 90,00% and not more than 110,00%. | en_US |
