Manfaat Jahe sebagai Terapi Tambahan pada Dispepsia Fungsional pada Remaja

Abstract

Background Functional dyspepsia is commonly occured among adolescents, however there is no standard treatment yet. Omeprazole is often used for functional dyspepsia. Ginger is one of complementary and alternative treatment in functional dyspepsia. Objective To investigate the use of ginger as an add-on therapy for functional dyspepsia in adolescent. Methods A randomized, single blind, controlled study was conducted from May until June 2012. Samples were divided into two groups, both groups received 20 mg of omeprazole once daily for 7 days. Intervention group received additional ginger 500 mg twice daily for 7 days, control group received placebo. Pain frequency was measured in pain episode in day per week, and duration was measured in minutes. Evaluation was done before, during and 1st and 2nd week after treatment. Data obtained was then analyzed by chi square and Friedman tests with the level of significance is 0.05. Results Sixty four from 878 (7.2%) patients suffered from functional dyspepsia. Fifty patients who fulfilled the inclusion and exclusion criteria were enrolled in this study, 24 patients in intervention group and 26 patients in control group. There was statistically significant difference in the frequency and duration of pain before, during and after treatment in both groups (P=0.0001 ). However, there was no statistically significant difference between intervention and control groups in the frequency and duration of pain. Conclusion Treatment with omeprazole is effective in reducing the frequency and duration of pain in functional dyspepsia. Ginger is not more effective than placebo as the add-on treatment of functional dyspepsia among adolescents