| dc.description.abstract | Background Functional dyspepsia is commonly occured among
adolescents, however there is no standard treatment yet. Omeprazole is often
used for functional dyspepsia. Ginger is one of complementary and
alternative treatment in functional dyspepsia.
Objective To investigate the use of ginger as an add-on therapy for
functional dyspepsia in adolescent.
Methods A randomized, single blind, controlled study was conducted from
May until June 2012. Samples were divided into two groups, both groups
received 20 mg of omeprazole once daily for 7 days. Intervention group
received additional ginger 500 mg twice daily for 7 days, control group
received placebo. Pain frequency was measured in pain episode in day per
week, and duration was measured in minutes. Evaluation was done before,
during and 1st and 2nd week after treatment. Data obtained was then analyzed
by chi square and Friedman tests with the level of significance is 0.05.
Results Sixty four from 878 (7.2%) patients suffered from functional
dyspepsia. Fifty patients who fulfilled the inclusion and exclusion criteria were
enrolled in this study, 24 patients in intervention group and 26 patients in
control group. There was statistically significant difference in the frequency
and duration of pain before, during and after treatment in both groups
(P=0.0001 ). However, there was no statistically significant difference between
intervention and control groups in the frequency and duration of pain.
Conclusion Treatment with omeprazole is effective in reducing the
frequency and duration of pain in functional dyspepsia. Ginger is not more
effective than placebo as the add-on treatment of functional dyspepsia among
adolescents | en_US |
