Hubungan Platelet Distribution Width dengan Kejadian Kardiovaskular Mayor selama Perawatan di Rumah Sakit pada Pasien Infark Miokard Akut ST Segmen Elevasi di Rumah Sakit Haji Adam Malik Medan

Abstract

The term "acute coronary syndrome" encompasses a range of thrombotic corona,y

artery diseases, including unstable angina and both ST-segment elevation and non- ST-Segment elevation myocardial infarction. Platelets play a vital role in

pathogenesis of atherosclerosis. Platelets are blood cells with diverse sizes and densities. In addition to an aggregation, platelets modulate important pathophysiological processes, including inflammation and coagulation. Larger platelets are considered to be more active. Platelet Distribution Width (PDvV) is an indication of the variation platelet sizes as a sign of active platelet. PDW can be an independent risk factor for cardiac death, non-fatal reinfarction, re-Percutaneous coronary intervention or coronary artery bypass grafting. In this retrospective study from medical record Acute Coronary Syndrome-STEM! patients in Adam lvf alik Hospital from 1 October until 31 December 2014, we found 69 patients which fu?fill inclusion and exclusion criteria. In 30 patients with PDW 2: 12, 7 JL, 39 patients with PDW < 12,7 JL. There is no association between high PDW level with in-hospital accident of Heart failure, Cardiac arrhythmia, Cardiogenic shock, or Cardiac death