| dc.description.abstract | Background : Fragmented QRS (fQRS) on the electrocardiogram (ECG) in
patients with acute ST segement elevation myocardial infarction (STEMI) will
have prognostic significance during hospitalization. The development of fQRS) is
related to defects in the ventricular conduction system and is linked to myocardial
scar and fibrosis.
Objective : This study aimed to detemine that fQRS can be used as a predictor in
predicting in hospital major adverse cardiac events (MACE) in STEMI patients.
Methods : the study was carried out using retrospectively collected data of 91
patients diagnosed as acute STEMI. fQRS group had fQRS both in admission and
latest ECGs (n= 46) and non-fQRS group had no fQRS in last ECG (n=45) further
recording of MACE in hospital.
. Results : From the analysis of the chi-square test found a significant correlation
between fQRS and mortality{RR 6,36 (Cl 95% 1,52 - 26,59) ,p=0,002}, fQRS
and arrhythmia { RR 5,87 (CI 95% 1,391 - 24,76),p = 0,004} and heart failure {
RR 2,087 (CI 95% 1,324 - 3,290),p = 0,001} and fQRS and MACE {RR 2,359
(IK 95% 1,6 - 3,479),p < 0,001}. No significant association between fQRS with
cardiogenic shock (p = 0,195). In the bivariate analysis there was a significant
relationship between age, systolic blood pressure (SBP) and heart rate with
MACE. The multivariate analysis only SBP and fQRS that would predict MACE
but fQRS was the most dominant variable in influencing of MACE {RR 16,058
(1K 95% 5,03-51,18),p = 0,0001}.
Conclusion : FQRS is a predictor for the occurrence of MACE (mortality,
arrhythmia and heart failure) during hospitalization in STEMI patients | en_US |
