Hubungan Kejadian Bakteriuria Asimtomatik dengan Kontrol Glikemik Pasien DM Tipe 2 di RSUP H Adam Malik Medan

Abstract

Background: The incidence of infection often occurs in patients with diabetes due to hyperglycemic that causes dysfunction chemotaxis, phagocytic activity, the malfunction of neutrophils and glycosuria. lt is followed by other complications that lead to malfunction of the bladder. Highly urinary glucose level is a good medium for pathogenic microorganisms growth. Asymptomatic bacteriuria (ASB) is a risk factor for symptomatic urinary tract infection spontaneously or due to urinary catheters. The aim of study: to analyze the association between the incidence of type 2 diabetes mellitus ASB and glycemic control. Methods: The study was conducted during June-August 2016 with cross sectional method. Subjects were Type 2 diabetes patients with age <60 yearS, whs weie trdated'on pblV El4doeririology of RSUP"I=IAM. 'F,[bA1c'Was measured by automalie analyzer lndiko, lts assseiatis,n with urine eultu!'e results was analyzed. Results: A total 50 samples were enrolled, consist of 25 women and 25 men, which 19 with good glycemic control (HbA1c <7o/o) and 31 with poor glycemic control (HbA1c >7%). Thirteen positive ASB were found; 5'with good glycemic control and 8 with poor glycemic control- Statistical analysis revealed a not significant association between glycemic control and culture results (p = 1.000). But it is significant differences in culture results between gender, where the ASB were found in samples of four women and two men (p = 0.004). Mogt of the bacteria foqnd wgrq gram-negative. Conclusions: There is no significant association between glycemic control with incidence of ASB. But gender has significantly differences on the incidence of ASB, which occurs more frequently in DM women than men. Screening urinalysis should be performed in patients with type 2 diabetes with ASB. However, further research is needed to analyze the relationship between glycemic control with incidence of ASB and other factors that may affect the ineidenee of ASB