Uji Diagnostik Mean Platelet Volume (MPV) terhadap Troponin T pada Kasus Sindroma Koroner Akut

Abstract

Introduction: Acute Coronary Syndrome (ACS) is used to describe the spectrum of coronary artery disease. Precise and rapid diagnosis can reduce morbidity and mortality. Troponin T is the determinant of the most sensitive marker in ACS but it is not all hospitals have this marker because of expensiveness. Mean Platelet Volume (MPV) is one of the components of a complete blood routine examination and relatively cheap as marker in ACS. Objective: To determine the sensitivity and specificity of MPV in detecting cases of acute coronary syndrome. Methods: Three hundred and twenty-five subjects research obtained from the medical records of patients hospitalized Adam Malik Hospital were collected during the period July 2013 to June 2014; 228 ACS patients met the inclusion criteria. Complete blood laboratory data collection and troponin T. Statistical analysis with diagnostic tests to see the accuracy of the MPV. Results: Following 228 subjects showed a risk factor for age 2: 45 years of more 195 (85,5%). 122 subjects with hypertension (53,5%) and subjects who smoked 118 (51,8%) that suffered most ACS. Subjects with risk factors for diabetes

mellitus, obesity, menopause and dyslipidemia in this study is lower than non- diabetic 161 (70,6%), obese 189 (82,9%), non menopause 196 (86%) and normal

Ii pig 210 (92, 1 % ). But there is not relation between risk factor with MPV and troponin T statistically. The results of diagnostic tests MPV for the evaluation of patients with ACS, sensitivity 92%, specificity 71 %, positive predictive value 95% and negative predictive value 58%. Conclusion: Examination MPV levels can be used for diagnostic test in ACS case. It has 92% and 71 % in sensitivity and specificity