| dc.description.abstract | Background: HbAlc levels were higher in patients with diabetes is associated with increased
risk of cardiovascular disease. Bilirubin is expected to act as an endogenous antioxidant and
anti-inflammatory. Increased serum bilirubin was associated with a reduced risk of coronary
heart disease and stroke.
Objective: To determine correlation of serum total bilirubin and HbAlc in controlled and
uncontrolled type 2 diabetes mellitus.
Methods: This study is a cross-sectional observational analytic approach performed in
RSUP.H.Adam Malik in February - March 2015. A sum of 50 samples were divided into 2
groups: Samples with controlled DM (HbAlc <7) and uncontrolled DM (HbAlc ?:_7)
amounted to 25 people each. All samples were examined serum total bilirubin.
Using statistical test unpaired student t test when distribution is normal, and if the distribution
is not normal, we use Mann Whitney test with a significance p value <0.05
Results: In this study we obtained serum levels of serum total bilirubin in patients with
HbAlc < 7 and HbAlc ?:_ 7 each 0.704 ± 0.299 and 0.560 ± 0.138. Although there are
differences, but we found no correlation between total bilirubin serum levels and HbA 1 c in
both groups (HbAlc <7, r = 0.119, p = 0.580 and HbAlc ?:_ 7, r = 0.234, p = 0.261)
Conclusions: There was no correlation between serum total bilirubin and HbA le in both
groups | en_US |
