| dc.description.abstract | Background : Anemia causes decreased oxygen carrying capacity, alterations in
blood viscosity, and impaired cerebral autoregulation and through its effects on
inflammation, anemia may be associated with poor outcome after stroke.
Mechanism relationship Chronic Kidney Disease (CKD) with worsening of stroke
outcome is unknown,but one study showed that increased aortic stiffness among
CKD patients was an explanation why CKD is a predictor of cerebrovascular
mortality.
Purpose : This study aims to compare outcomes among anemia patients with
CKD and anemia without CKD in patients with subacute ischemic stroke.
Methods : This cross sectional study consisted of 70 patients with subacute
ischemic stroke; 35 anemia patients with CKD and 35 anemia patients without
CKD. All subjects who have inclusion criterias will be assessed the outcome with
National Institute Of Health Stroke Scale (NIHSS) and Modified Rankin Scale
(mRS) on the 14th day after treatment.
Results : In this study it was found that the difference in outcome with a
significant positive correlation between anemic patients with CKD and anemia
without CKD in patients with ischemic stroke sub-acute (p = 0. 038, r = 0. 329 in
NIHSS and p = 0.013, r = 0.286 on the mRS). On examination NIHSS and mRS,
it was found a significant association with positive correlation with the strength of
the relationship of each strong and weak between the degree of anemia with
outcomes in with subacute ischemic stroke patients with CKD (p = 0.001,
r = 0.688; p = 0.009, r = 0.291) and it was found a significant relationship with a
positive correlation with the strength of the relationship was moderate on the
NIHSS and mRS examination in anemia patients without CKD (p = 0.001,
r = 0.585; p = 0.002, r = 0.404). It was also found a significant correlation with the
positive correlation with moderate strength between the degree of CKD and the
outcome, both in the NIHSS examination (p = 0. 003, r = 0.490) as well as on the
mRS examination (p = 0.003, r = 0.489).
Conclusion : There was significant difference in outcome between patients with
anemia with CKD and anemia without CKD in subacute ischemic stroke | en_US |
