Gambaran Histologi Pankreas Mencit (Mus Musculus L.) Jantan Yang Diberi Limbah Degumming Kokon Ulat Sutera (Bombyx mori L.) yang telah dipapar Obat Nyamuk Elektrik

Abstract

Research of the histology of the male mice (Mus musculus L.) pancreas exposed to electric mosquito and then given by degumming silkworm cocoon’s (Bombyx mori L.) waste had been carried out from December 2022 to March 2023. The waste of degumming Silkworm cocoons contain sericin has the potential to omit the free radicals due to its antioxidant activity. The research method used a completely randomized design (CRD) consisted of 5 treatments: exposure only to electric mosquito coils; electric mosquito coils and vitamin C; electric mosquito coils and degumming of silkworm cocoons at doses of 100 mg/kg, 200 mg/kg and 300 mg/kg. This study used 25 male mices (Mus musculus L.). The observations were done to the pancreatic histology including the diameter of the islets of Langerhans, the damage to necrosis, the vacuolization and the pancreatic congestion. The research results showed degumming silkworm cocoons (Bombyx mori L.) had a significant effect on improving the diameter of the islets of Langerhans and the necrosis of the pancreas, but no significant differences in vacuolization and congestion pancreas.