| dc.description.abstract | Background : Global experience of managing patients with COVID-19-related
acute respiratory distress syndrome (ARDS) is growing rapidly, along with an
increasing number of reports on respiratory system mechanics and ventilator
management. Over the past two decades, ARDS heterogeneity has become
increasingly recognized, and efforts have been made to describe subgroups of
patients with different clinical and biological characteristics, clinical outcomes,
and treatment responses. Given the importance of mechanical ventilation of lung
protectors in ARDS. With the increase in COVID-19 cases, the purpose of this
study is how the relationship of the severity of symptoms, d-dimer and pao2/FiO2
ratio in blood gas analysis of ards incidence in COVID 19 patients at RSUP H
Adam Malik Medan, North Sumatra.
Method: The design of this study is analytical research with cross sectional
design using data on the medical records of patients diagnosed as COVID-19
patients with ARDS and non-ARDS who are treated in the isolation room of
Adam Malik Hajj Central General Hospital.
Results : In this study, in terms of the severity of symptoms, there was a
meaningful relationship (p=0.000). It was later found a significant association
between d-dimer levels in early admission patients with ARDS incidence in
COVID-19 patients and a 7.3 times higher risk of d-dimer being ARDS, according
to the Mert O et all study. In older age (>40 years) can not be meaningful relationships (p = 0.284), but older age is more experienced ARDS. Results :
There is no meaningful relationship between age, gender, cough, loss of smell,
loss of taste, fever, nausea, myalgia, colds, diarrhea, smoking habits, comorbid
factors, PaO2/FiO2 ratio of ARDS incidence. Then, there is a link between
shortness of breath, severity of symptoms and d-dimer values against ARDS
events. Thoracic photos cannot be assessed because all research subjects have
bilateral infiltrates. Then there was the meaningful relationship between the sexes
and the incidence of ARDS (p=0.005), men at 3.8 times higher risk of becoming
ARDS. In terms of complaints, shortness of breath and loss of smell are quite
significant (p=0.000, p=0.000), not by coughing, loss of taste, fever, nausea,
muscle aches, chest pain, colds, and diarrhea (p=0.312, p=1,000, p=0.750,
p=1,000, p=0.059, p=0.460, p=0.255, p=0.589, respectively). There was a
significant association between smoking habits and ARDS incidence and when
further analysis was conducted, patients with smoking habits 2.8 times developed
into ARDS compared to non-smoking patients. The thoracic photo relationship to
ards events cannot be assessed because all research subjects have bilateral
infiltrates. The relationship of comorbid factors to ARDS events, 29 of which
were found to be comorbid, but statistically, there is no meaningful relationship
between comorbid factors and ARDS events.
Conclusion: There is no meaningful relationship between age, cough, loss of
smell, loss of taste, fever, nausea, muscle pain, colds, diarrhea, smoking habits,
comorbid factors, PaO2/FiO2 ratio there is an incidence of ARDS. Then, there is a
meaningful relationship between the severity of symptoms, d-dimer values,
gender and shortness of breath to the incidence of ARDS. Thoracic photos cannot
be assessed because all research subjects have bilateral infiltrates. | en_US |
