Perbedaan Kadar Feritin pada Gastritis Anak dengan dan Tanpa Infeksi Helicobacter Pylori

Abstract

Background: Gastritis is one of the most common gastrointestinal health problems and is divided into acute and chronic gastritis. Where the main cause of chronic gastritis is infection with Helicobacter pylori bacteria, while ferritin levels play a role in the inflammatory process in the body, one of which is gastritis which is defined as an inflammatory process (inflammation) in the gastric mucosa and submucosa, which occurs in response to acute and chronic damage. which ultimately leads to mucosal atrophy and epithelial metaplasia. Objective: To determine the difference in ferritin levels in gastritis in children with and without Helicobacter pylori infection. Methods: Cross sectional study in outpatients and inpatients in 2 places from September 2020 to March 2021. The diagnosis of Helicobacter pylori gastritis was confirmed by the CLO test. Blood samples were taken from the subjects to evaluate ferritin levels. Results: A total of 60 study subjects with gastrointestinal complaints, subjects were divided into 2 groups based on the CLO test, 29 subjects with Helicobacter pylori infection and 31 subjects without Helicobacter pylori infection. The results of the study showed that the average ferritin level in children with H. Pylori infection (+) was 63.52 mcg/L (SD = 43.79 mcg/L) and the average ferritin level in the group of children with H. pylori infection (-) was 50.24 mcg/L (SD = 43.29 mcg/L). By using the Mann Whitney test, it was found that there was no difference in ferritin levels in gastritis in children with and without H. pylori infection (p=0.139). Conclusion: there is no difference in ferritin levels in gastritis in children with and without H. pylori infection.