Hubungan Kadar Asam Laktat dengan Derajat Dehidrasi terhadap Kondisi Usus pada Pasien Invaginasi Anak

Abstract

Background : Several recent studies have indicated that there is a significant relationship between the level of lactic acid in the blood and the level of dehydration in pediatric patients who experience invagination. Lactic acid, produced as a byproduct of anaerobic metabolism, has been shown to be a sensitive indicator in evaluating tissue oxygenation levels and mitochondrial function. Increased lactic acid production in the setting of intestinal invagination may reflect the presence of tissue hypoxia associated with dehydration Method : This research is observational analytic with a cross sectional approach using secondary data from medical records of the Department of Surgery, Pediatric Division, Haji Adam Malik Hospital, Medan. This research was conducted at the Haji Adam Malik General Hospital, Medan in August 2023, while the medical records used were medical records for the period 01 January 2018 to 31 July 2023. Result : The results showed that regarding viable intestinal conditions, 4 people (50%) had normal lactic acid levels, 4 people (50%) had hyperlactaemic lactic acid levels. In non-viable intestinal conditions, 11 people (73.3%) had hyperlactaemia lactic acid levels and 4 people (26.7%) had severe lactic acidosis. The p value obtained was 0.008 (p<0.05) which can be interpreted as meaning that there is a significant relationship between lactic acid levels and intestinal conditions in pediatric invagination patients. Conclusion : From this study, there was a relationship between lactic acid levels and the degree of dehydration on intestinal conditions in pediatric invagination patients (p<0.05). Measurement of lactic acid can provide valuable information for the medical team in planning appropriate treatment at the right time. Measurement of lactic acid levels in the blood can provide important clues about the severity of dehydration and the potential severity of intestinal invagination in pediatric patients.