Hubungan Global Longitudinal Strain (GLS) Ventrikel Kiri Preoperatif terhadap Kejadian Kardiovaskular Mayor (KKVM) Selama Rawatan dan Fraksi Ejeksi Ventrikel Kiri Pasca Operasi Katup Mitral pada Pasien Regurgitasi Mitral Berat di RSUP Haji Adam Malik Medan

Abstract

Background: Mitral regurgitation (MR) is the second most common cause of heart valve abnormalities in developing countries. Severe nonoperative RM conditions are associated with high mortality and morbidity. Knowing of left ventricle Global Longitudinal Strain (LV GLS) can provide predictive data on postoperative complications of severe MR patients who will undergo mitral valve surgery. The purpose of this study was to find relationship between preoperative LV GLS and Mayor Cardiovascular Events (MACE) and LVEF during hospitalization after surgery. Hasil : Subyek penelitian berjumlah 40 orang, berjenis kelamin laki-laki berjumlah 16 orang (40%). Rerata nilai GLS VKi preoperatif -18,12% ± 5,79. Pasca operasi sebanyak 3 orang (7,5%) meninggal akibat kardiovaskular, gagal jantung akut terjadi pada 14 orang (35%). Rerata FEVKi post operasi 38,71% ± 12,58. Analisa bivariat dengan chi square diperoleh nilai GLS VKi ≤-17,1% preoperatif berhubungan signifikan dengan KKvM dan FEVKi selama rawatan pasca operasi dengan nilai berturut-turut OR=0,134 dan OR=1,85 (p<0.05). Kesimpulan : Terdapat hubungan yang signifikan antara GLS VKi pre operatif dengan. KKvM dan FEVKi selama rawatan pasca operasi pada pasien RM berat yang menjalani operasi katup mitral Method: This is an analytic observational study with ambispective in severe MR patients undergoing mitral valve surgery in January 2021 to October 2023. The criteria for severe MR are using American Society of Echocardiography (ASE) guidelines. Bivariate analysis is investigating relationship between preoperative LV GLS and MACE and LVEF with p<0.05 was considered statistically significant. Results: The study subjects are 40 people, male 16 patients (40%). The mean preoperative LV GLS was -18,12% ± 5.79. After surgery 3 people (15.8%) have cardiac death, heart failure occurred in 14 people (35%). Average postoperative LVEF is 38.71% ± 12.58. Bivariate analysis with chi square show preoperative LV GLS values were significantly associated with MACE and LVEF during postoperative hospitalization with OR=0.134 and OR=1,85 (p<0.05) respectively. Conclusion: There is a significant relationship between preoperative LV GLS and MACE and LVEF during postoperative care in severe MR patients undergoing mitral valve surgery