Uji Aktivitas Antioksidan dari Ekstrak Etanol Daun Cempedak (Artocarpus champeden) dengan Metode DPPH

Abstract

Background: Plants are one source of bioactive compounds that have the potential to be used as medicine. Indonesia is a mega biodiversity country with an abundance of medicinal plants that have the potential to be developed as traditional medicine products. Testing using DPPH will produce information regarding antioxidant activity in warding off free radicals which is seen based on the IC50 value and the resulting data needs to be compared with other compounds that have good antioxidant activity. Objective: This study aims to determine the antioxidant activity of the ethanol extract of cempedak leaves (Artocarpus champeden) using the DPPH method. Method: Testing the antioxidant activity of the ethanol extract of cempedak leaves was carried out using the DPPH method. Results: The ethanol extract of cempedak leaves had an IC50 antioxidant activity of 10.2813 with a regression equation Y = 3.8331x + 10.5905 and a correlation coefficient of 0.9608 μg/ml. Conclusion: Based on the results of research that has been carried out, it was found that the ethanol extract of cempedak leaves has an IC50 antioxidant activity of 10.2813 μg/ml which is categorized as very strong because it has a value of less than 50 μg/ml.