| dc.description.abstract | important factors, including follicular epidermal hyperproliferation, increased
sebum production, increased activity of C. acnes and inflammation. Increased
sebum levels can increase the production of porphyrins which appear as redorange
fluorescence on the faces of patients with acne vulgaris.
Objective: To determine the correlation between sebum levels and follicular
fluorescence in acne vulgaris patients.
Subjects and Methods: This study was an observational analytic study with cross
sectional data collection method involving 60 acne vulgaris patients based on
inclusion and exclusion criteria. Basic data were recorded including age and
gender. Sebum levels were measured using a Sebumeter® SM 815 (C & K,
Courage-Khazaka, Cologne, Germany) and follicular fluorescence was examined
using a Visiopor® PP34 camera (C & K, Courage-Khazaka, Cologne, Germany).
The correlation between sebum levels and follicular fluorescence was analyzed
using Spearman correlation. The result was significant if the p value<0.05.
Results: Acne vulgaris was more common in women (76.7%) with a mean age of
22.52 years, the youngest was 18 years old and the eldest was 36 years old. The
results of this study showed a positive correlation with moderate strength between
sebum levels and the spot counts (r = 0.495) and positive correlation with weak
strength between sebum levels and the percentage of the area covered with
follicular fluorescence spots (r = 0.349).
Conclusion: There is a correlation between sebum levels and follicular
fluorescence in acne vulgaris patients. | en_US |
