Hubungan antara Nilai D-Dimer dengan Mortalitas pada Anak dengan Covid-19 di Rumah Sakit Kota Medan Provinsi Sumatera Utara

Abstract

Background: D-dimer is a fibrin degradation product that can be used as a parameter of coagulopathy in Covid-19 patients and is associated with the incidence of ARDS, the need for ICU care and death. Objective: To determine the relationship between D-dimer values and mortality in children with Covid-19 in Medan City Hospitals, North Sumatera. Methods: Observational analytical study with a retrospective cohort design of children confirmed for Covid-19 based on PCR who were treated in the isolation ward at H. Adam Malik Hospital, Bunda Thamrin Hospital and Murni Teguh Hospital, Medan. The relationship between D-dimer values and mortality was seen in children aged 0-18 years and analyzed using the Fischers Exact Test. Results: From a multivariate analysis with 155 subjects, it was found that the Ddimer value had no correlation with mortality (p=0,006) but it was found that shortness of breath was at risk of death 36 times greater than children who did not have shortness of breath. Conclution: The D-dimer value has no relationship with mortality in children with confirmed Covid-19.