Efektivitas Oral Wound Dressing Film Berbasis Propolis Trigona sp. terhadap Penyembuhan Luka secara Klinis Pasca Diinduksi Luka Gingiva pada Tikus Wistar (Rattus norvegicus)

Abstract

Wounds on the gingiva can occur due to improper tooth brushing technique or the scraping of gingiva from nail scratches. The healing of gingival wounds is a dynamic process that is essential in meeting the patient’s needs. Therefore, the application of oral wound dressing film (OWDF) is required to cover the wound and minimize the risk of complications. Propolis of Trigona sp. is effective in accelerating the healing of the wound due to its antibacterial, anti-inflammatory and antioxidant properties. The aim of this study is to determine the effectiveness of Trigona sp. propolis based OWDF on clinical wound healing post gingival wound induction on Wistar rats. This study is an experimental laboratory study that is conducted in vivo and utilizes a post-test control group design to assess clinical parameters with the Hagenaars et al. healing indices. The sample consisted of 24 healthy female Wistar rats, all of which are aged 2-3 months. The results of the study revealed the effect of Trigona sp. propolis based OWDF on clinical wound healing after 14 days on the propolis group in comparison to the control group. Samples within the propolis group showcased rapid re-epithelialization, contraction and wound healing as opposed to the control group during the two-week study period. Thus, the Trigona sp. propolis based OWDF has proved to be effective in gingival wound healing.